|Taken from In Old Kentucky, a History of My Forbears|
Isaac was a respected farmer and a man of tireless energy; he was numbered among the wealthy and influential citizens of Rush County. He helped to found the Christian Church at Manilla and remained a faithful member there throughout his life. Isaac was also a member of the Knights of Pythias. At two different times, he was tendered a nomination to the legislature of the Democratic party, but Isaac chose instead to live a quiet life in his Rush County home.
However, Isaac's second son, John William Inlow, was his undoing. John was a man with big ideas... and a spendthrift. He had great visions of doubling his father's assets. John invested a great deal of his father's money in real estate in Indianapolis. According to the Indianapolis Journal, on March 14, 1871, John purchased a lot for $2,300. (That's roughly equivalent to $45,000 today!) Then, his scheme backfired, and John lost his father's money. Isaac was forced to to sell the Manilla farm in 1879. John ended up as a floorwalker at the New York Store (aka Pettis Dry Goods Co.) in Indianapolis, a position he held for many years.
After he lost his farm, Isaac and his wife moved 50 miles away to Alexandria, Indiana, where his oldest son, James Elliott Inlow, was practicing as a doctor. When James relocated to Hancock County, Isaac and Lucinda returned to Manilla. In 1894, Lucinda Inlow died. At the time of her death, she was completely blind. It then fell upon the youngest son, George Jefferson Inlow, to care for his elderly father. George worked as both a carpenter and a druggist in Manilla. Isaac Inlow died at George's home, at the age of 89, from a stroke.
(Much of the biographical information in this blogpost comes from the book In Old Kentucky, a History of My Forbears, Book 3 by William DePrez Inlow, published in 1950.)